Avalos initially ran for the Portland City Commission in the 2020 election, announcing her run in August 2019.[5] She was defeated by Carmen Rubio in the primary, receiving only 8.9 percent of the vote compared to Rubio's 67.6 percent.[6]
In September 2023, Avalos announced her run for the newly expanded city council in the 2024 election, running in District 1, which represents East Portland.[7] Avalos was endorsed by former Governor Kate Brown, Multnomah County Chair Jessica Vega Pederson, and the Service Employees International Union, along with her former opponent Rubio.[3] Avalos had the most endorsements out of the candidates elected[8] and was the only candidate endorsed by all 4 major papers Portland Mercury, Willamette Week, The Oregonian, and The Skanner. Avalos easily led the race in the initial round, receiving 19 percent of the first place vote against 16 other candidates.[9] Local news agencies quickly called the race for Avalos.[10]
On January 2, 2025, Avalos ran for the presidency of the new City Council, but was defeated by Elana Pirtle-Guiney after ten rounds of voting.[11]