Carreón made the White Sox for good in 1961, getting into 78 games, with 63 starts at catcher in relief of 37-year-old veteran star Sherm Lollar. He hit a two-run single off Whitey Ford to give Juan Pizarro a 2–1 victory over the New York Yankees on August 15, 1961. The second-inning hit enabled the White Sox to break Ford's 14-game winning streak.[3] Overall, he hit .271 in his first full MLB season. The next year, 1962, he supplanted Lollar as the White Sox' regular catcher, starting 85 games and hitting .256. His best big-league season came in 1963, when he played in 101 games and hit .274, starting 81 games behind the plate. It was his last full and healthy season in the majors.
Indians and Orioles
The White Sox placed Carreón on the disabled list on July 3, 1964, after he tore tendons in his right arm.[4] During the 1964–65 offseason, Chicago traded him to the Cleveland Indians as part of a blockbuster three-way trade involving the Kansas City Athletics that also included Rocky Colavito, Tommy John and Tommie Agee. Going into the 1965 campaign, Carreón was listed as the Indians' second-string catcher, behind Joe Azcue.[5] But he played only 19 games with the Tribe, spent 45 games back in Triple-A with Portland of the Pacific Coast League, and was one of five players assigned outright to Portland in October 1965.[6]
Cleveland then traded Carreón to the Orioles during spring training of 1966 in a one-for-one deal for Lou Piniella, then a 22-year-old, minor league outfielder in the Baltimore organization. The Orioles were en route to their first-ever American League pennant that season, but Carreón got into only four games for Baltimore (his last on June 8, when he hit a double in his final MLB at bat), and spent the latter half of the year with Triple-A Rochester. He played two more minor league seasons before retiring from baseball.
As a major leaguer, Carreón collected 260 hits, including 43 doubles, four triples, and 11 home runs, with 114 runs batted in. He batted .264 lifetime. Defensively, he recorded a .993 fielding percentage as a catcher, committing only 13 errors in 1,776 total chances. He died in Tucson, Arizona, at the age of 50, and is buried in the Hermosa Memorial Cemetery in Colton.[7]