Along with "You've Got a Killer Scene There, Man...", it borrows heavily from the blues. ZZ Top's guitarist and singer Billy Gibbons appears on lead guitar and backup vocals. Gibbons also plays on a cover of his own band's "Precious and Grace", a bonus track on the album.
The song involves an exchange of vocal lines between the falsetto of Homme and the twin baritones of Gibbons and Mark Lanegan. Gibbons does not regularly tour with the band, so the other vocal was performed by Lanegan, until he stopped touring with the band. Currently, Josh Homme sings alone with backing vocals from the rest of the band. In the previous line-up, Homme played bass and Alain Johannes played a quite different version of Gibbons' solo. This song (its remix by UNKLE) was also featured in and on the soundtrack of Saw II. This song is also featured in the trailer to the fourth season of the HBO series True Blood and in Peaky Blinders.