Baxley appeared in supporting roles in many television series of the 1950s, 1960s, and 1970s. She played a wife who had her rodeo performer husband, played by Lee Van Cleef, murdered in the crime drama series Richard Diamond, Private Detective, starring David Janssen. She appeared in a 1958 Perry Mason episode, "The Case of the Gilded Lily", as Enid Griffin and she played the role of Cora Wheeler in the original Twilight Zone episode of "Mute".
Another Baxley performance came in a 1973 episode of Hawaii Five-O entitled "One Big Happy Family". She portrayed the matriarch of a serial-killing family.
She is perhaps better known for the role of Lady Pearl, the feisty wife of country music icon Haven Hamilton (Henry Gibson) in Robert Altman's film Nashville (1975) and as the mother of Sally Field's character in Norma Rae (1979).
Baxley was a close friend of musician Dave Brubeck and his wife; according to him, Baxley was more like a member of the family.[3] He later confirmed that Baxley was a liberalDemocrat, an atheist, a woman who always put the needs and well-being of others before her own self, and that when she died, he and his wife, Iola, not only handled her funeral arrangements but also buried her in the same cemetery next to their own plots so that they all could be together as one in death, same as in life, because their bond held such a strong connection.[3]