BMC Systems Biology was an open accesspeer-reviewedscientific journal that covered research in systems biology. Filling a gap in what was a new research field, the journal was established in 2007 and is published by BioMed Central.[1] Part of the BMC Series of journals, it had a broad scope covering the engineering of biological systems, network modelling, quantitative analyses, integration of different levels of information and synthetic biology.[2]
In January 2019, the Editorial Board was informed that the journal was closing and no more submissions would be accepted after March 1.[3] The last articles were published on 5 April 2019, but content is still archived in perpetuity from the homepage and PubMed Central.[citation needed]
Scope and Coverage
BMC Systems Biology focused on a wide range of topics within systems biology, including but not limited to:
Engineering of biological systems
Network modelling
Quantitative analyses
Integration of different levels of information
Synthetic biology
The journal provided a platform for the dissemination of significant research findings in the area of systems biology, aiming to bridge the gap between biological research and mathematical modelling.[4]
Notable Articles and Research
Several significant studies were published in the journal, contributing to the advancement of systems biology. Some notable research includes:
"A quantitative systems pharmacology (QSP) model for Pneumocystis treatment in mice"[5]
"Network-based characterization of drug-protein interaction signatures with a space-efficient approach"[6]
"Boolean network modeling of β-cell apoptosis and insulin resistance in type 2 diabetes mellitus"[7]
Impact and Legacy
The journal's impact factor in 2018 was 2.048, reflecting its influence and relevance in the field of systems biology.[8] Although the journal is now closed, its archived content continues to serve as a valuable resource for researchers and scholars.
