She studied piano, and began writing lyrics and dancing since early childhood.[2]
In 2004, she released her debut single, entitled "Kizuna", which was used as opening theme for the TV anime series W Wish.[1] Her first moderate success came in 2007 with her 5th single, "Nageki no Mori", which was used as the opening theme of the PlayStation 2 game Higurashi: When They Cry – Matsuri[1] and became her first Top 30 entry on the Oricon charts.[3]
In 2009, her 8th single "Lunatic Tears...", which was used as theme song for the computer game 11eyes: Tsumi to Batsu to Aganai no Shōjo, received high acclaim and won the Gold Prize in the theme song category at the Bishojo Game Awards.[1]
In 2014, she released her third studio album, Luminous Flux, and later released her 10th anniversary commemorative album Base Ten, for which she included re-arranged versions of previous singles, self-covers, and anime covers.[4] This year she was also invited to numerous international anime-related events, and performed live in Russia,[5] the United States[6] and Taiwan.[7]
In November 2016, her 23rd single "Soul Buster" was used as theme song of the Chinese-Japanese co-produced anime of the same name.[7]
In 2019, she celebrated the 15th anniversary with the release of the EP for Dearest, whose leading song was used as theme song for the video game Memories off -Innocent Fille-, and also held her 15th anniversary concert Ayane 15th Anniversary Live -for Dearest- at Club Seata in Kichijoji, Tokyo.[7]
In 2020, Ayane was appointed to perform the ending theme song for the Higurashi: When They Cry – Gou anime.[8] She subsequently also performed the second ending theme of Gou,[9] and the opening theme of the final season Higurashi: When They Cry – Sotsu in 2021.[10]