Growing up in the city of Kotka, Kuier was discovered for basketball by a neighbour at age 10, when she stood already 180 cm tall. The man contacted Mikko Kokkola, who was coaching basketball at the local Peli-Karhut [fi], and Kokkola invited her to practice.[8] Kuier joined the club. She was named the U16-league Player of the Season in 2015–16. She debuted in top-tier Naisten Korisliiga with PeKa first team in the 2016–17 season.[9] At the age of 14, a video of her dunking went viral online.
In 2017, at the age of 16, she joined the Helsinki Basketball Academy team HBA-Märsky.[10] Kuier played in Naisten Korisliiga with HBA team, and was named the Most Improved Player in the league in 2019. She was also named the league's Player of the Month in January 2020.[11]
Selected 2nd overall in the 2021 WNBA draft by the Dallas Wings, she was the first non-American player since Australia's Liz Cambage in 2011 to be selected in the first five picks of the draft.[13] After missing the first few games of the 2021 season, she made her debut for the Wings on 27 May 2021, scoring a point, a rebound, and an assist in seven minutes of game time in a 101–95 loss to the Atlanta Dream.[14] In addition to her speed and resilience, Kuier's features also include an exceptionally large wingspan of about seven feet.[15] On June 10, 2022, in a game against the Seattle Storm, Kuier became the 8th woman in WNBA history to dunk a basketball.
On January 22, 2024, Kuier announced that she will skip the 2024 WNBA season.[3] This is due to overlapping seasons between Italy and the United States, and the strict change in WNBA rules concerning absences related to playing in Europe.[16][17] Kuier has stated that her dream is to compete in the EuroLeague Women.
In May 2024, Kuier helped Reyer Venezia to win the Italian championship title. She was also named the Finals MVP with her 24-point performance in the decisive third final match.[18] The team also advanced to the semi-finals of the EuroCup. In July 2024, Kuier extended her contract with Venezia.[19][20][21] In September, she was named the Best Foreign Player in the Italian league.[22]
On 10 October 2024, Kuier made her debut in the EuroLeague for Venezia, recording 14 points, six rebounds, three assists and two blocks in a 80–59 win over Hungarian UNI Győr.[23][24]
She was born in Cairo, Egypt and is of South Sudanese origin.[2] She moved to Finland as a refugee with her family when she was two years old,[26] first settling in the city of Kotka.[27] Today, her family has settled in the coastal town of Uusikaupunki and she holds dual Finnish and Egyptian citizenship.[28][29] She speaks Italian, Arabic, Finnish, and English.[30] Kuier has four older brothers and her parents are Jehovah's Witnesses.[31][2] Kuier and her family are close friends with Federiko Federiko and his family, who share a similar background.[32][33]