In 2012, Markopoulou was appointed to the faculty at the University of California, Irvine. Her research group, the UCI Networking Group, considers mobile data analytics, privacy and the internet of things.[3] Markopoulou has looked to understand advertising and tracking services, and train machine learning models for the detection and blocking of advertising.[4][5] She co-founded Shoelace Wireless, an app that speeds up mobile internet by combining Wi-Fi and cellular networks.[6]
In 2020, Markopoulou was awarded $10 million from the National Science Foundation to study personal information, data and security.[7] The program, ProperData: Protecting Personal Data Flow on the Internet, seeks to protect personal data on mobile devices.[8][9] She was the first Samueli School of Engineering researcher to be appointed Chancellor's Fellow at the University of California, Irvine in 2019.[10]
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