The team first competed in the Arizona League (AZL) from 1998 to 2002.[2] The team played at facilities in Tucson from 1998 to 2000, and Phoenix from 2001 to 2002. The team was formed after the major-league Chicago White Sox moved their spring training headquarters from Sarasota, Florida, to Tucson Electric Park after the 1997 season. The move effectively transplanted their Rookie-level Gulf Coast League White Sox across the country to the Arizona League. The AZL White Sox compiled a record of 115–161 (.417) during their first incarnation, never posting a winning mark.
The team departed the Arizona League in 2003, and was absent from the league for 11 seasons.[3][4]
The White Sox' Rookie-level team has competed in Arizona since 2014.[2] The team shares the Camelback Ranch stadium with the Arizona League Dodgers, whose parent team, the Los Angeles Dodgers, also train at the Glendale facility. Prior to the 2021 season, the Arizona League was renamed as the Arizona Complex League (ACL).