Alfredo Barbieri was born in Montevideo to José and Mariana (née Romano) Barbieri. He had a hesitant start to his ecclesiastical career as his parents were strongly opposed to his becoming a priest. Before entering the consecrated life. Barbieri worked as an insurance clerk.[1] He joined the Order of Friars Minor Capuchin on December 8, 1913, and was later sent to Genoa, Italy, to continue his novitiate in 1915. Receiving the habit on the following September 8, Barbieri made his solemn vows and took the nameAntonio María.
He then attended Capuchin houses of study and the Pontifical Gregorian University in Rome. Barbieri was ordained on December 17, 1921, and obtained his doctorate in theology from the Gregorian on July 9, 1923. He declined a professorship at a prestigious university in Rome and returned to Uruguay, where he served as a pastor in the local Capuchin friary. He was elected superior of this mission in 1931 and re-elected five years later.
On October 6, 1936, Barbieri was appointed coadjutor bishop of Montevideo and titular bishop of Macra. He was consecrated on the following November 8 by Archbishop Filippo, with Archbishop Giovanni Aragone and Bishop Alfredo Violas serving as co-consecrators.
He was one of the cardinal electors in the 1963 conclave, participated in the Second Vatican Council (1962–1965), and during the 1960s was recognized for his long periods of service as a theologian and historian with his promotion to the Instituto Histórico y Geográfico del Uruguay (Historical and Geographical Institute of Uruguay). Barbieri resigned as Montevideo's archbishop on November 17, 1976, after thirty-five years of service. He died on July 6, 1979, at age 86.