Angela Casini

Angela Casini
Alma materUniversity of Florence
AwardsEuropean Medal for Bio-Inorganic Chemistry
Scientific career
InstitutionsTechnical University of Munich
University of Groningen

Angela Casini is a medicinal and inorganic chemist who works on metal-based compounds as therapeutic agents. She was awarded the 2012 European Medal for Bio-Inorganic Chemistry and made the 2019 American Chemical Society Inorganic Lecturer.

Early life and education

[1] She earned her PhD in chemical sciences at the University of Florence in 2004.[2] She was a postdoctoral fellow at the University of Pisa, where she worked on the mechanisms by which metal-complexes that are used as anti-cancer agents activate.[1] She used both spectroscopy, including mass spectrometry imaging, and molecular biology.[1]

Research and career

Angela Casini joined the École Polytechnique Fédérale de Lausanne as a Principal Investigator in 2008.[3] She moved to the University of Groningen in 2011, where she was made a Rosalind Franklin Fellow.[4] She was made a Chair of Medicinal Chemistry at Cardiff University in 2015, and has served as Director of Postgraduate Teaching from 2018.[5] She spent 2016 as a visiting professor at the Technical University of Munich.

Awards and honours

Her awards and honours include;

Selected publications

Her publications include;

  • Casini, Angela (2003). "Carbonic anhydrase inhibitors". Medicinal Research Reviews. 23 (2): 146–189. doi:10.1002/med.10025. PMID 12500287. S2CID 90349277.
  • Casini, Angela (2004). "Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH". FEBS Letters. 577 (3): 439–445. doi:10.1016/j.febslet.2004.10.043. PMID 15556624. S2CID 37646843.
  • Casini, Angela (2004). "Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition". Journal of Medicinal Chemistry. 47 (3): 550–557. doi:10.1021/jm030912m. PMID 14736236.

Casini serves on the editorial board of the Journal of Biological Inorganic Chemistry and the Journal of Inorganic Biochemistry.

References

  1. ^ a b c Gabbiani, Chiara; Casini, Angela; Messori, Luigi (2007-03-01). "Gold(III) compounds as anticancer drugs". Gold Bulletin. 40 (1): 73–81. doi:10.1007/BF03215296. ISSN 2190-7579.
  2. ^ Medicinal, Professor Angela Casini Chair of; Chemistry, Bioinorganic. "Professor Angela Casini - People". Cardiff University. Retrieved 2019-08-26.
  3. ^ Casini, Angela; Woods, Benjamin; Wenzel, Margot (2017-12-18). "The Promise of Self-Assembled 3D Supramolecular Coordination Complexes for Biomedical Applications". Inorganic Chemistry. 56 (24): 14715–14729. doi:10.1021/acs.inorgchem.7b02599. ISSN 0020-1669. PMID 29172467.
  4. ^ "Institute for Advanced Study (IAS): Casini, Angela". www.ias.tum.de. Retrieved 2019-08-26.
  5. ^ "The School of Chemistry welcomes new staff member Professor Angela Casini". Cardiff University. Retrieved 2019-08-26.
  6. ^ "EuroBIC". www.bioinorganic-chemistry.org. Retrieved 2019-08-26.
  7. ^ "2014 Metals in Medicine Conference GRC". www.grc.org. Retrieved 2019-08-26.
  8. ^ "Angela Casini". metallomics2017.univie.ac.at. Retrieved 2019-08-26.
  9. ^ "Angela Casini – Young Academy of Europe". 18 December 2016. Retrieved 2019-08-26.
  10. ^ "Burghausen Chemistry Award for Angela Casini". www.tum.de. Retrieved 2019-08-26.
  11. ^ "Burghausen Chemistry Award for Angela Casini". www.tum.de. Retrieved 2019-08-26.
  12. ^ "Angela Casini Receives 2019 Inorganic Chemistry Lectureship Award". ACS Axial. 2019-03-12. Retrieved 2019-08-26.
  13. ^ Medicinal, Professor Angela Casini Chair of; Chemistry, Bioinorganic; PGT, Director of. "Prof Angela Casini wins 2019 Inorganic Chemistry Lectureship Award". Cardiff University. Retrieved 2019-08-26.