Andrés Mendoza may refer to:

• Andrés Mendoza (Mexican footballer) (born 1995), Mexican football midfielder
• Andrés Hurtado de Mendoza, 3rd Marquis of Cañete (c. 1500–1561), Spanish military officer and fifth viceroy of Peru
• Andrés Mendoza (Peruvian footballer) (born 1978), Peruvian football player
• Andrés Mendoza (Ecuadorian footballer) (born 1989), Ecuadorian football player
• Andrés Mendoza (serial killer) (born 1949), Mexican serial killer

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