After completing her postdoctoral training, Brunstein-Klomek returned to Israel, where she joined the Interdisciplinary Center Herzliya. She has shown that frequent exposure to bullying can increase a young person's risk of suicidal ideation and depression.[4] She has described cyberbullying as a major public health problem, and proposed that school students should be taught both resilience and how to conduct themselves.[5] She has argued that all members of society can play a role in bullying prevention, and that adults and parents in particular can be transformative for victimised children.[6] Brunstein-Klomek has used interpersonal psychotherapy to support adolescents with attention deficit hyperactivity disorder and specific learning differences.[7][8]
Since 2015 Brunstein-Klomek has been involved with the Israel National Suicide Prevention plan, through which she has worked on programmes for Palestinian and Israeli people.[9] The programme has helped teachers, parents and counsellors have conversations with school students.[10] Brunstein-Klomek has investigated the impact of internet use in people diagnosed with eating disorders.[11] As part of this work, Brunstein-Klomek showed that despite people with eating disorders accessing pro-ana websites, it is possible to redirect them to useful websites which can help.[11] During the COVID-19 pandemic, Brunstein-Klomek became concerned about the provision of mental health services to at-risk groups. Writing in The Lancet, Brunstein-Klomek called for suicide prevention to be integrated into the global response to the pandemic. She argued that during and after the extended periods of mandatory social isolation at-risk populations may be at a greater risk of suicidal ideology.[12]
^Klomek, Anat Brunstein; Stanley, Barbara (7 November 2014). "Psychosocial Treatment of Depression and Suicidality in Adolescents". CNS Spectrums. 12 (2): 135–144. doi:10.1017/S1092852900020654. PMID17277714. S2CID45355324.