Amanda Paulovich

Amanda Paulovich
Alma materCarnegie Mellon University
University of Washington
AwardsHUPO Distinguished Achievement in Proteomic Sciences Award (2015)
Scientific career
FieldsBiology
InstitutionsFred Hutchinson Cancer Research Center
Thesis The Regulation of S Phase Progression Rate in Yeast in Response to DNA Damage  (1996)
Doctoral advisorLeland H. Hartwell

Amanda Grace Paulovich is an oncologist, and a pioneer in proteomics using multiple reaction monitoring mass spectrometry to study tailored cancer treatment.

Education

Paulovich received a BS in Biological Sciences from Carnegie Mellon University in 1988,[1] a PhD in Genetics from University of Washington in 1996, under the direction of Leland Hartwell.[2] She also received a MD from University of Washington in 1998.[3] Follow her residency in Internal Medicine at Massachusetts General Hospital, she also completed a Postdoctoral Fellowship in Computational Biology at the Massachusetts Institute of Technology Whitehead Center for Genomic Research in 2003, and a Fellowship in Medical Oncology at the Dana Farber Cancer Institute in 2004.[1][4]

Career

Paulovich is a Professor in Clinical Research, an Aven Foundation Endowed Chair, and the Director of Early Detection Initiative at the Fred Hutchinson Cancer Research Center.[5][6] She was inducted to the American Society for Clinical Inviestigation in 2012.[7]

Paulovich is an expert in proteomics.[8] Her targeted proteomics method uses multiple reaction monitoring mass spectrometry to target cancer biomarkers with ongoing clinical trials,[9] and was named Method of the Year in 2012 by Nature Methods.[10][11] She founded Precision Assays in 2016,[12] whose rights to targeted assays were acquired by CellCarta in 2022.[13][14]

Awards

Patent applications

  • Identification and use of biomarkers for detection and quantification of the level of radiation exposure in a biological sample (2011) US 20130052668 A1[19]
  • Compositions and methods for reliably detecting and/or measuring the amount of a modified target protein in a sample (2011) US 20130052669 A1[20]

References

  1. ^ a b "Amanda Paulovich, M.D., Ph.D." Fred Hutch. Retrieved 2022-06-06.
  2. ^ "UW Genome Sciences: Alumni". www.gs.washington.edu. Retrieved 2022-06-06.
  3. ^ "Alumni Directory | Medical Scientist Training Program". Retrieved 2022-06-06.
  4. ^ "Doctors Dr. Amanda G. Paulovich MD". U.S. News & World Report. Retrieved June 6, 2022.
  5. ^ "MCS Alumna Develops New Technologies for Early Cancer Detection". Carnegie Mellon University Carnegie Mellon Today Archives. September 1, 2004. Retrieved June 6, 2022.
  6. ^ Pittsburgh, A. Carnegie Mellon University Publication 5000 Forbes Avenue; Pa 15213268-2000. "MCS Alumna Develops New Technologies for Early Cancer Detection". Carnegie Mellon Today. Retrieved 2022-06-06.{{cite web}}: CS1 maint: numeric names: authors list (link)
  7. ^ "The American Society for Clinical Investigation". Archived from the original on 2022-10-18. Retrieved 2022-06-08.
  8. ^ "Interviewer List | Biocompare: The Buyer's Guide for Life Scientists". www.biocompare.com. Retrieved 2022-06-08.
  9. ^ "CPTAC Contributes to the Identification of a Novel Pharmacodynamic Biomarker for Clinical Trial Use | Office of Cancer Clinical Proteomics Research". proteomics.cancer.gov. Retrieved 2022-06-08.
  10. ^ "Beyond genomics: Using proteomics to target tumors". ScienceDaily. Retrieved 2022-06-08.
  11. ^ "Fred Hutch's Paulovich lab to lead protein assay work for Beau Biden Cancer Moonshot". American Association for the Advancement of Science (AAAS) EurekAlert! Archive. 2017-02-06. Retrieved 2022-06-08.
  12. ^ "PRECISION ASSAYS, LLC :: Washington (US) :: OpenCorporates". opencorporates.com. Retrieved 2022-06-08.
  13. ^ "CellCarta Acquires Next-Generation Immuno-MRM Assays from Precision Assays". CellCarta. Retrieved 2022-06-08.
  14. ^ CellCarta. "CellCarta expands it proteomics portfolio with the acquisition of next-generation immuno-MRM assays from Precision Assays". www.newswire.ca. Retrieved 2022-06-08.
  15. ^ "Pappu recognized as 'woman to watch' in life science". WSU Insider. Retrieved 2022-06-06.
  16. ^ "MSACL-Paulovich". www.msacl.org. Retrieved 2022-06-06.
  17. ^ "HUPO - Past Award Recipients". www.hupo.org. Retrieved 2022-06-06.
  18. ^ "SCIEX Partners with the Paulovich Lab at Fred Hutchinson Cancer Research Center to Advance Cancer Research Reproducibility". www.businesswire.com. 2015-09-22. Retrieved 2022-06-06.
  19. ^ US application 20130052668A1  Amanda G. Paulovich, Richard G. Ivey/Fred Hutchinson Cancer Research Center: "Identification and use of biomarkers for detection and quantification of the level of radiation exposure in a biological sample" filing date 29.04.2011
  20. ^ US application 20130052669A1  Amanda G. Paulovich, Richard G. Ivey/Fred Hutchinson Cancer Research Center: "Compositions and methods for reliably detecting and/or measuring the amount of a modified target protein in a sample" filing date 29.04.2011

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