In 2001, Wright was cast as Laverne Roberts in the NBC comedy series, Scrubs. After six seasons, her character was killed off in "My Long Goodbye". She returned in season seven playing a new character, Nurse Shirley. She later returned to play Nurse Roberts in the season 8 finale, "My Finale", as JD is looking back on all the people in his life. In 2000s, Wright also guest starred on NYPD Blue, Cold Case, NCIS, and Mad Men. She also had supporting parts in films such as Bring It On, The Brothers, Mr. Deeds and Johnson Family Vacation.
In 2008, Wright began appearing as nurse Maxine Landis in the NBC daytime soap opera, Days of Our Lives.[2] From 2012 to 2013, Wright also had the recurring role as Mildred Clemons in the Shonda Rhimes' series, Private Practice, and in 2015 appeared in an episode of Scandal. In 2015, she joined the cast of USA Network legal series Suits for season five as Harvey Specter’s new secretary, Gretchen Bodinski.[3][4] She appeared on the show in a recurring basis until the series finale aired in 2019. In 2020, she was cast as Viola, the title character's grandmother in the Nickelodeon sitcom Young Dylan created by Tyler Perry.[5]