From an early age Alípio de Miranda-Ribeiro had a passion for natural history; as an adolescent he translated works of Buffon into Portuguese. He studied medicine in Rio de Janeiro, and from 1894 worked as a preparator at the National Museum of Brazil. Here he later served as secretary (from 1899), and director of the department of zoology (from 1929).
During his career he explored the Amazon region many times, and under the direction of Candido Rondon (1865–1958) he took part in installing the first telegraph through the Amazon and Mato Grosso. In 1911, after visiting museums and fishery programs in Europe and the United States, he founded a fisheries inspectorate in Brazil, the first official services on fisheries in the nation.
In 1911 he published the highly regarded Fauna brasiliensis-Peixes (Brazilian fishes). He was also the author of numerous works in the field of herpetology.
Taxa named in his honor
The genus of trematode parasites of amphibians Ribeiroia is named after him.