Penava was a reserve player during his first two seasons with the Herd. He had his breakout season as a junior when he became a full-time starter. One of his best games came against the Ohio Bobcats where he had 33 points, 15 rebounds, and 9 blocks in a 99–96 win.[1] He would later help lead Marshall to an upset win against Wichita State in the 2018 NCAA tournament scoring 16 points, grabbing 8 rebounds, and blocking 3 shots.[2] Penava led the nation in blocks during 2017–18 season and decided to declare for the 2018 NBA draft at season's end. He initially did not sign with an agent, but decided to do so on April 19. He did not return to Marshall for his senior season.[3]
Penava played for the Bosnian national team during the 2015 FIBA Europe Under-18 Championship. Penava averaged 5.6 ppg and 4.8 rpg during the tournament.