It was Casimir's second marriage and occurred two years after the death of his first wife, Aldona of Lithuania. His union with Aldona had produced two daughters, Elizabeth (1326–1361) and Kunigunde (also Cunigunde; 1334–1357), but no male heirs.
Adelaide was seventeen or eighteen years old at the time of the wedding – only a few years older than Casimir's eldest daughter – and Casimir was 31. The marriage was an unhappy one and Casimir started living separately from Adelaide soon after their marriage. Adelaide lived primarily at the castle in Żarnowiec on the Pilica river and is credited with founding the parish church there.
Their loveless marriage lasted until 1356. Casimir separated from Adelaide in 1356 and entered a morganatic marriage with his mistress, Krystyna Rokiczana (also Christina), the widow of Mikulasz Rokiczani (also Miklusz, Mikuláš), a wealthy merchant. Casimir's separation from Adelaide was not recognized by the church and was considered bigamous, which put him at odds with the clergy.
Casimir continued living with Krystyna despite complaints by Pope Innocent VI on behalf of Adelaide. The marriage lasted until 1363 or 1364, at which time Casimir again declared himself divorced. They had no children. The marriage to Adelaide was annulled in 1368. Then Casimir married his fourth wife, Jadwiga (Hedwig) of Żagań.
This marriage produced another three daughters.
With Adelaide still alive and Christina possibly as well, the marriage to Jadwiga was also considered bigamous. The legitimacy of the three last daughters was disputed. Casimir managed to have two of his daughters, Anna and Kunigunde, legitimatised by Pope Urban V on December 5, 1369. Jadwiga the younger, was legitimatised by Pope Gregory XI on October 1, 1371.
Later life
After the annulment of her marriage, Adelaide went back home to Hesse. She spent the rest of her life in Hesse.
After her ex-husband's death, she fought for her property rights. She intervened in this case to Pope Gregory XI. On May 26, 1371, the Pope urged King Louis to give back her property.