Higginbotham began his career in television by submitting a spec script for Will & Grace, and from 2005 to 2006, served as a producer for the show. In 2007, he served as co-executive producer for Back to You and in 2008 served as an executive producer for Do Not Disturb. Since 2010, Higginbotham has served as a consulting producer for Family Guy, wrote for and produced for Ugly Betty and executive producer and writer for Modern Family.
In November 2018, it was announced that Higginbotham had co-created an upcoming comedy, Happy Accident for ABC, on which he would serve as executive producer and writer.[3] The series, however, was passed on by the network.[4] In August 2022, Higginbotham executive produced and cowrote 2 episodes of the Netflix series Uncoupled starring Neil Patrick Harris.