In 2017, Shampklin scored his first career touchdown against Rhode Island. He finished the year with 363 rushing yards and three TDs.
In 2018, Shampklin played in all 10 games and was named first team All-Ivy League. He scored four touchdowns against San Diego along with a career-high 178 rushing yards. Shampklin finished with 1,053 rushing yards on 173 carries and nine touchdowns
In 2019, Shampklin would not play due to injury.
In 2020, the Ivy League cancelled their football season.
In 2021, Shampklin was name all-Ivy League for a second time. He ran for 835 yards and 11 touchdowns.
Shampklin signed with the Dallas Cowboys as an undrafted free agent on May 3, 2022.[3] He was placed on injured reserve on August 31, 2022.[4] He was then released on September 2, 2022.[5]
Indianapolis Colts
On December 20, 2022, Shampklin signed with the Indianapolis Colts practice squad.[6] He signed a reserve/futures contract on January 9, 2023.[7] He was released on May 2.[8]
Houston Gamblers
On May 18, 2023, Shampklin signed with the Houston Gamblers of the USFL. In three games with the Gamblers, Shampklin ran for 52 yards on 12 attempts. He was released on August 1.
Shampklin signed a reserve/futures contract with the Pittsburgh Steelers on January 17, 2024.[11] He was waived on August 27 and signed to the practice squad on September 4.[12][13] He was elevated to the active roster ahead of the Steelers Week 4 matchup with the Indianapolis Colts, in which he made his NFL debut.[14] He was released on October 28, 2024, and re-signed to the practice squad.