Callie Morgan (Samantha Mathis), a workaholic magazine editor who prides herself on having no emotional attachments in her life, changes practically overnight when she undergoes a life-saving heart transplant operation. Not only does Callie find herself strangely drawn to a young girl who happens to be the heart donor's orphaned daughter, but she also finds unlikely romance with another patient who also recently received a new heart. She soon discovers that the man, named Jasper Cates (Peter Dobson), received the heart from her donor's husband.