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A27 motorway
Αυτοκινητόδρομος 27
Route information
Length	78.5 km (48.8 mi)
Major junctions
North end	North Macedonia border
South end	Kozani
Location
Country	Greece
Regions	West Macedonia
Major cities	Kozani, Ptolemaida, Florina
Highway system
Highways in Greece Motorways National Roads

The A27 motorway is a branch of the A2 Egnatia Odos motorway at Kozani, which leads towards Ptolemaida and from there to Florina and the Niki border crossing with North Macedonia. It is part of the European route E65.

Within 2012 tenders were announced for the construction of the 14,5 km section from Florina up to the border crossing with North Macedonia as a motorway.^[1] Construction started in 2013 and finished in December 2015. The northern part from Florina to Niki was opened to traffic on 20 May 2016. The section from Ptolemaida to Florina is operational as an expressway (GR-3) and is planned to be upgraded to a motorway sometime until 2025.

This article contains a bulleted list or table of intersections which should be presented in a properly formatted junction table. Please consult this guideline for information on how to create one. Please improve this article if you can. (November 2021)

Regional unit	Exit	Name	Destinations	Notes/Also as
Florina		Niki border crossing (North Macedonia)	E65  North Macedonia	Northern terminus of the A27
		Kato Kleines-Ano Kalliniki		E65
		Florina	GR-2 E86 GR-3	E65
		Vevi North	GR-2 E86 GR-3	Expressway/Upgrade planned E65
		Vevi South	GR-2 E86 GR-3	Expressway/Upgrade planned E65
		Xino Nero		Expressway/Upgrade planned E65
		Amyntaio		Expressway/Upgrade planned E65
		Vegoritida	GR-2 E86 to Edessa	Expressway/Upgrade planned E65
		Filotas		Expressway/Upgrade planned E65
Kozani		Perdikkas		Expressway/Upgrade planned E65
		Ptolemaida North		E65
		Ptolemaida South	GR-3	E65
		Pontokomi	GR-3	E65
		Kozani Interchange	A2 E90 to Ioannina, Thessaloniki GR-3 E65 to Larissa	Southern terminus of A27