The men's 50m breaststroke events at the 2022 World Para Swimming Championships were held at the Penteada Olympic Swimming Complex in Madeira between 12 and 18 June.

Event	Gold	Silver	Bronze
SB2	José Arnulfo Castorena  Mexico	Grant Patterson  Australia	Jesús Hernández Hernández  Mexico
SB3	Efrem Morelli  Italy	Miguel Luque Ávila  Spain	Takayuki Suzuki  Japan

Heats

13 swimmers from ten nations took part. The swimmers with the top eight times, regardless of heat, advanced to the final.^[1]

Rank	Heat	Lane	Name	Nation	Result	Notes
1	2	4	José Arnulfo Castorena	Mexico	1:00.83	Q
2	1	4	Jesús Hernández Hernández	Mexico	1:02.99	Q
3	2	5	Grant Patterson	Australia	1:04.13	Q
4	2	3	Cristopher Tronco Sánchez	Mexico	1:04.36	Q
5	2	6	Ioannis Kostakis	Greece	1:06.86	Q
6	1	3	Emmanuele Marigliano	Italy	1:08.09	Q
7	1	5	Charkorn Kaewsri	Thailand	1:10.18	Q
8	1	6	Daniel Robles Ferrer	Spain	1:18.93	Q
9	2	2	Gabriel Araújo	Brazil	1:20.76
10	1	2	Patricio Tse Anibal Lopez Fernandez	Dominican Republic	1:44.52
11	2	7	Bruno Becker da Silva	Brazil	1:47.12
12	2	1	Jacob Brayshaw	Canada	1:54.67
13	1	7	Amr Abdalla	Egypt	2:13.65

Final

The final was held on 12 June 2022.^[2]

Rank	Name	Nation	Result	Notes
	José Arnulfo Castorena	Mexico	59.55
	Grant Patterson	Australia	1:03.58
	Jesús Hernández Hernández	Mexico	1:04.02
4	Emmanuele Marigliano	Italy	1:06.59
5	Ioannis Kostakis	Greece	1:08.20
6	Charkorn Kaewsri	Thailand	1:14.03
7	Daniel Robles Ferrer	Spain	1:14.73
	Cristopher Tronco Sánchez	Mexico	DSQ