Singles
2022 Open Sopra Steria de Lyon
Final
Champion	Corentin Moutet
Runner-up	Pedro Cachin
Score	6–4, 6–4
Events
Singles Doubles
← 2021 · Open Sopra Steria de Lyon · 2023 →

Pablo Cuevas was the defending champion^[1] but chose not to defend his title.

Corentin Moutet won the title after defeating Pedro Cachin 6–4, 6–4 in the final.

	Semifinals							Final
	8	Manuel Guinard	3	2
	7	Corentin Moutet	6	6
								7	Corentin Moutet	6	6
									Pedro Cachin	4	4
		Pedro Cachin	6	7
	2	Richard Gasquet	1	5

	First round							Second round							Quarterfinals							Semifinals
	1	F Coria	6	6
	Q	K Coppejans	3	3				1	F Coria	78	78
	Q	A Fils	77	4	6			Q	A Fils	66	66
		C Ugo Carabelli	65	6	4										1	F Coria	4	2
		A Pellegrino	6	6											8	M Guinard	6	6
		GA Olivieri	4	4					A Pellegrino	4	5
	WC	U Blanchet	5	3				8	M Guinard	6	7
	8	M Guinard	7	6																		8	M Guinard	3	2
	3	H Dellien	3	1																		7	C Moutet	6	6
		H Grenier	6	6					H Grenier	6	6
	Q	I Gakhov	6	6				Q	I Gakhov	2	1
	WC	L Van Assche	2	4												H Grenier	3	6	63
		E Furness	6	6											7	C Moutet	6	4	77
	Q	J Shang	2	3					E Furness	4	4
		A Ritschard	2	63				7	C Moutet	6	6
	7	C Moutet	6	77

	First round							Second round							Quarterfinals							Semifinals
	5	N Borges	6	6
		G Lama	4	4				5	N Borges	4	2
		F Díaz Acosta	65	3					A Müller	6	6
		A Müller	77	6												A Müller	64	65
		P Cachin	77	6												P Cachin	77	77
	WC	K Jacquet	65	4					P Cachin	4	6	77
	LL	JB Torres	6	6				LL	JB Torres	6	2	61
	4	P Andújar	3	3																			P Cachin	6	7
	Q	G Décamps	6	6																		2	R Gasquet	1	5
		T Seyboth Wild	2	3				Q	G Décamps	5	1
	Q	A Vatutin	6	6				Q	A Vatutin	7	6
	LL	M Janvier	4	2											Q	A Vatutin	1	6	1
		A Collarini	6	6											2	R Gasquet	6	3	6
		J Sels	4	4					A Collarini	77	4	2
		G Barrère	4	6	1			2	R Gasquet	62	6	6
	2	R Gasquet	6	4	6

• Main draw
• Qualifying draw