Singles
2022 Mexico City Open
Final
Champion	Marc-Andrea Hüsler
Runner-up	Tomás Martín Etcheverry
Score	6–4, 6–2
Events
Singles Doubles
Mexico City Open · 2023 →

This was the first edition of the tournament.^[1]

Marc-Andrea Hüsler won the title after defeating Tomás Martín Etcheverry 6–4, 6–2 in the final.

	Semifinals							Final
		Marc-Andrea Hüsler	77	6
		Felipe Meligeni Alves	65	2
									Marc-Andrea Hüsler	6	6
								2	Tomás Martín Etcheverry	4	2
	7/WC	Nicolás Jarry	6	5	64
	2	Tomás Martín Etcheverry	3	7	77

	First round							Second round							Quarterfinals							Semifinals
	1	F Bagnis	3	2
		JP Ficovich	6	6					JP Ficovich	4	1
		M-A Hüsler	3	6	6				M-A Hüsler	6	6
	Q	Gilbert Klier Júnior	6	3	4											M-A Hüsler	6	6
		M Janvier	6	77												M Janvier	3	3
	WC	LC Álvarez	3	62					M Janvier	3	6	77
		G Oliveira	5	78	3			5	JI Londero	6	3	65
	5	JI Londero	7	66	6																		M-A Hüsler	77	6
	4	A Martin	2	1																			F Meligeni Alves	65	2
		J de Jong	6	6					J de Jong	0	6	3
		R Olivo	6	4	77				R Olivo	6	2	6
	Q	N Chappell	4	6	62											R Olivo	65	3
	Q	K Smith	6	3	4											F Meligeni Alves	77	6
	Alt	P Krstin	4	6	6			Alt	P Krstin	1	4
		F Meligeni Alves	1	77	6				F Meligeni Alves	6	6
	6	E Escobedo	6	65	2

	First round							Second round							Quarterfinals							Semifinals
	7/WC	N Jarry	4	77	6
	Alt	V Durasovic	6	65	2			7/WC	N Jarry	77	6
		M Pucinelli de Almeida	5	77	78				M Pucinelli de Almeida	65	2
	Alt	D Istomin	7	65	66										7/WC	N Jarry	77	7
		F Mena	1	6	3											G Melzer	64	5
	Q	N Barrientos	6	2	6			Q	N Barrientos	1	1
		G Melzer	6	0					G Melzer	6	6
	3	S Kozlov	4	0r																		7/WC	N Jarry	6	5	64
	8	J Clarke	6	63	6																	2	TM Etcheverry	3	7	77
	Alt	B Tomic	4	77	3			8	J Clarke	5	3
		F Gaio	3	6	4			Q	M Alves	7	6
	Q	M Alves	6	3	6										Q	M Alves	1	1
	Q	Elmar Ejupovic	6	6											2	TM Etcheverry	6	6
	WC	A Hernández	4	4				Q	E Ejupovic	1	62
		E Donskoy	3	2				2	TM Etcheverry	6	77
	2	TM Etcheverry	6	6

• Main draw
• Qualifying draw