Singles
2021 Zagreb Ladies Open
Final
Champion	Anhelina Kalinina
Runner-up	Kamilla Rakhimova
Score	6–1, 6–3
Events
Singles Doubles
← 2020 · Zagreb Ladies Open · 2022 →

Ana Konjuh was the defending champion^[1] but chose to compete in Madrid instead.

Anhelina Kalinina won the title, defeating Kamilla Rakhimova in the final, 6–1, 6–3.

	Semifinals							Final
	PR	Alexandra Dulgheru	4	5
	4	Kamilla Rakhimova	6	7
								4	Kamilla Rakhimova	1	3
									Anhelina Kalinina	6	6
		Anhelina Kalinina	6	6
	Q	Jessica Pieri	2	0

	First round							Second round							Quarterfinals							Semifinals
	1	E Cocciaretto	4	6	710
		R Šramková	6	3	68			1	E Cocciaretto	4	1
	PR	A Dulgheru	6	6				PR	A Dulgheru	6	6
	LL	F Arcidiacono	0	1											PR	A Dulgheru	1	6	6
	PR	I Khromacheva	4	6	4										5	K Kučová	6	2	1
		A Gasanova	6	4	6				A Gasanova	5	2
	WC	M Đaković	1	4				5	K Kučová	7	6
	5	K Kučová	6	6																		PR	A Dulgheru	4	5
	4	K Rakhimova	6	4	6																	4	K Rakhimova	6	7
		L Pattinama Kerkhove	1	6	0			4	K Rakhimova	6	2	7
	Q	T Mrdeža	2	6	6			Q	T Mrdeža	4	6	5
	Q	A Prisăcariu	6	3	3										4	K Rakhimova	6	4	6
	WC	J Fett	6	6											WC	J Fett	3	6	4
	WC	L Bošković	2	1				WC	J Fett	6	6
	Q	RL Jani	6	6				Q	RL Jani	4	3
	LL	M Benoît	1	2

	First round							Second round							Quarterfinals							Semifinals
	6	K Nara	4	3
	WC	P Marčinko	6	6				WC	P Marčinko	1	2
	Q	J Niemeier	6	79				Q	J Niemeier	6	6
	Q	D Jakupović	4	67											Q	J Niemeier	5	4
		A Kalinina	6	65	6											A Kalinina	7	6
		M Bolkvadze	3	77	2				A Kalinina	60	6	6
	JE	D Parry	6	5	6			JE	D Parry	77	3	2
	3	K Kawa	4	7	4																		A Kalinina	6	6
	7	B Haas	65	6	6																	Q	J Pieri	2	0
		C Bucșa	77	1	2			7	B Haas	6	6
	Q	T Würth	6	4	77			Q	T Würth	3	4
	Q	R Marino	4	6	64										7	B Haas	2	7	1
	Q	J Pieri	2	6	6										Q	J Pieri	6	5	6
		M Di Giuseppe	6	2	2			Q	J Pieri	4	77	6
		E-G Ruse	6	6					E-G Ruse	6	65	3
	2	G Minnen	3	1

• Main Draw