290 Avtodor 81–74 Zielona Góra (11 December 2021) Excluding the games played without fans due to the COVID-19 pandemic, including the games played with restricted attendance for the same reason
A total of 10 teams from three countries contest the league, including eight sides from Russia, one from Belarus, and one from Kazakhstan.[1]
BC Khimki didn't apply for this season because of the financial difficulties.[2]
On 24 February 2022, Estonian club Kalev/Cramo terminated their membership in the VTB United League in protest against the Russian invasion of Ukraine.[3] The next day the league confirmed receiving declaration letter from the club.[4] On 25 February, Polish club Zielona Góra also suspended their participation in the competition.[5][6] On 1 March, VTB United League released a statement "Zielona Góra has suspended participation in the League at the moment, the next three home games have been postponed".[7]
Source: VTB United League Legend: Blue = home team win; Red = away team win.
Playoffs
Quarterfinals, semifinals, and bronze medal series were played in a best-of-five format (2-2-1). Finals were played in a best-of-seven format (2-2-1-1-1).