The 2021–22 Southend United F.C. season is the club's 116th season in their history and the first season in the National League following their second successive relegation. Along with the National League, the club will also participate in the FA Cup and FA Trophy.
The season saw a change in manager and first team coaches following the sacking of Phil Brown. Kevin Maher was recruited as first team coach, as well as multiple notable backroom-staff appointments, including former player, Stan Collymore as Senior Football Strategist and John Still as Head of Football.
The season covers the period from 1 July 2021 to 30 June 2022.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
Source: National League official site Rules for classification: 1) Points; 2) Goal difference; 3) Number of goals scored; 4) Number of matches won; 5) Head-to-head results[50]