^On April 5, 2021, Wofford announced that it was opting out of the remainder of the spring 2021 season as a result of injuries and player opt-outs due to COVID-19.[2] This game was postponed, with the makeup date still to be announced, at the time of its cancellation.
^On March 29, 2021, Chattanooga announced that it would opt out of the remainder of the 2021 spring season due to safety concerns related to the COVID-19 pandemic.[3]