The 2018–19 Liga Națională is the 61st season of Liga Națională, the Romanian top-level women's professional handball league. The league comprises 14 teams. CSM București are the defending champions, for the fourth season in a row.
^Roman withdrew from the championship in the first part of the season and all their results were canceled.[1][2]
Promotion/relegation play-offs
The 3rd and 4th-placed teams of the Divizia A promotion tournament faced the 11th and 12th-placed teams of the Liga Națională. The first two places promoted to Liga Națională and the last two relegated to Divizia A. The play-offs were played on neutral ground, in Cisnădie.