The 2015–16 Copa del Rey was the 6th staging of the Copa del Rey de Futsal. The competition started on 22 September with First Round matches. The Final was held in Seville at Pabellón de San Pablo on 1 May 2016.
Movistar Inter was the defending champion but lost in Quarter-finals to Palma Futsal.
Eventually, ElPozo Murcia won its first ever Copa del Rey title after defeating Palma Futsal 3–2 in the Final.
Draw will take place on 24 September at RFEF headquarters. Draw included ten winners from the first round plus all Primera División and 6 remaining Segunda División teams.
Round of 16 draw was held on Friday 2 October at RFEF headquarters. This round draw includes the 16 winners from the Second Round, which in summary are 11 teams from Primera División, 3 from Segunda División and 2 from Segunda División B.