Men's singles
2012 Mutua Madrid Open
Final
Champion	Roger Federer
Runner-up	Tomáš Berdych
Score	3–6, 7–5, 7–5
Events
Singles men women Doubles men women
← 2011 · Mutua Madrid Open · 2013 →

Roger Federer defeated Tomáš Berdych in the final, 3–6, 7–5, 7–5 to win the men's singles tennis title at the 2012 Madrid Open. With the win, Federer won his record-tying 20th Masters title and third title at Madrid.

Novak Djokovic was the defending champion, but lost to Janko Tipsarević in the quarterfinals.

This was the first and only edition of the tournament to be held on blue clay courts.

The top eight seeds receive a bye into the second round.

	Quarterfinals							Semifinals							Final
	1	Novak Djokovic	62	3
	7	Janko Tipsarević	77	6
								7	Janko Tipsarević	2	3
								3	Roger Federer	6	6
	3	Roger Federer	6	6
	5	David Ferrer	4	4
															3	Roger Federer	3	7	7
															6	Tomáš Berdych	6	5	5
	10	Juan Martín del Potro	6	6
	16	Alexandr Dolgopolov	3	4
								10	Juan Martín del Potro	65	66
								6	Tomáš Berdych	77	78
	6	Tomáš Berdych	6	6
	15	Fernando Verdasco	1	2

	First round							Second round							Third round							Quarterfinals
								1	N Djokovic	6	2	6
	Q	D Gimeno Traver	77	4	6			Q	D Gimeno Traver	2	6	3
	Q	V Hănescu	63	6	3										1	N Djokovic	77	6
		O Rochus	4	64												S Wawrinka	65	4
		S Wawrinka	6	77					S Wawrinka	6	6
		J Melzer	3	78	6				J Melzer	1	4
	13	F López	6	66	4																	1	N Djokovic	62	3
	9	G Simon	61	6	6																	7	J Tipsarević	77	6
		F Fognini	77	3	3			9	G Simon	6	6
		M Baghdatis	4	6	4			WC	G García López	4	3
	WC	G García López	6	3	6										9	G Simon	63	7	1
		A Ramos	3	2											7	J Tipsarević	77	5	6
	Q	F Delbonis	6	6				Q	F Delbonis	65	78	3
								7	J Tipsarević	77	66	6

	First round							Second round							Third round							Quarterfinals
								3	R Federer	4	7	77
		M Raonic	6	6					M Raonic	6	5	64
		D Nalbandian	4	4											3	R Federer	6	6
		V Troicki	6	4	6										14	R Gasquet	3	2
		D Young	1	6	1				V Troicki	5	3
		T Bellucci	6	4	65			14	R Gasquet	7	6
	14	R Gasquet	4	6	77																	3	R Federer	6	6
	11	N Almagro	65	6	6																	5	D Ferrer	4	4
	Q	S Giraldo	77	3	3			11	N Almagro	6	77
		M Granollers	7	3	7				M Granollers	3	63
		C Berlocq	5	6	5										11	N Almagro	65	6	68
		R Štěpánek	6	7											5	D Ferrer	77	3	710
		B Tomic	2	5					R Štěpánek	64	2
								5	D Ferrer	77	6

	First round							Second round							Third round							Quarterfinals
								8	J Isner	64	63
	WC	A Montañés	3	3					M Čilić	77	77
		M Čilić	6	6												M Čilić	2	4
		M Youzhny	6	6											10	JM del Potro	6	6
	WC	J Martí	3	2					M Youzhny	4	61
		F Mayer	4	2				10	JM del Potro	6	77
	10	JM del Potro	6	6																		10	JM del Potro	6	6
	16	A Dolgopolov	77	6																		16	A Dolgopolov	3	4
		P Andújar	65	4				16	A Dolgopolov	65	77	6
		M Llodra	5	4					A Seppi	77	65	3
		A Seppi	7	6											16	A Dolgopolov	7	3	77
	Q	S Stakhovsky	63	65											4	J-W Tsonga	5	6	62
	WC	R Harrison	77	77				WC	R Harrison	2	64
								4	J-W Tsonga	6	77

	First round							Second round							Third round							Quarterfinals
								6	T Berdych	6	6
		K Anderson	6	6					K Anderson	4	3
		A Bogomolov Jr.	3	2											6	T Berdych	6	6
	Q	I Andreev	6	77											12	G Monfils	1	1
		JC Ferrero	4	64				Q	I Andreev	3	0r
		P Kohlschreiber	5	77	3			12	G Monfils	6	1
	12	G Monfils	7	62	6																	6	T Berdych	6	6
	15	F Verdasco	7	6																		15	F Verdasco	1	2
		D Istomin	5	2				15	F Verdasco	64	6	6
	Q	A Falla	6	2	6			Q	A Falla	77	4	4
		JI Chela	3	6	2										15	F Verdasco	6	3	7
		I Karlović	64	3											2	R Nadal	3	6	5
		N Davydenko	77	6					N Davydenko	2	2
								2	R Nadal	6	6

	First round							Qualifying competition
	1	Santiago Giraldo	78	6
	WC	Marius Copil	66	1
								1	Santiago Giraldo	1	6	6
									Daniel Muñoz de la Nava	6	4	2
		Daniel Muñoz de la Nava	6	6
	10	Philipp Petzschner	3	2

	First round							Qualifying competition
	2	Alejandro Falla	6	6
	WC	Hasier Pastor	2	2
								2	Alejandro Falla	6	77
									Íñigo Cervantes-Huegun	3	63
		Íñigo Cervantes-Huegun	6	3	77
	11	Adrian Ungur	3	6	65

	First round							Qualifying competition
	3	Sergiy Stakhovsky	4	6	6
	WC	Iván Navarro	6	4	1
								3	Sergiy Stakhovsky	6	4	7
								8	Édouard Roger-Vasselin	2	6	5
		Peter Torebko	62	2
	8	Édouard Roger-Vasselin	77	6

	First round							Qualifying competition
	4	Flavio Cipolla	6	7
		Éric Prodon	4	5
								4	Flavio Cipolla	3	6	5
								13	Victor Hănescu	6	3	7
		Eduardo Schwank	3	2
	13	Victor Hănescu	6	6

	First round							Qualifying competition
	5	Matthew Ebden	2	63
		Frederico Gil	6	77
									Frederico Gil	5	4
								14	Daniel Gimeno Traver	7	6
		Arnaud Clément	0	1
	14	Daniel Gimeno Traver	6	6

	First round							Qualifying competition
	6	Potito Starace	5r
	WC	Adam Sanjurjo Hermida	4
								WC	Adam Sanjurjo Hermida	2	2
									Federico Delbonis	6	6
		Federico Delbonis	7	78
	12	Vasek Pospisil	5	66

	First round							Qualifying competition
	7	Igor Andreev	6	6
		Michael Berrer	2	2
								7	Igor Andreev	3	6	6
									Roberto Bautista Agut	6	3	4
		Roberto Bautista Agut	78	78
	9	Björn Phau	66	66

• Main Draw
• Qualifying Draw^{[permanent dead link‍]}