Wheelchair women's singles
2010 US Open
Final
Champion	Esther Vergeer
Runner-up	Daniela Di Toro
Score	6–0, 6–0
Events
Singles men women boys girls Doubles men women mixed boys girls WC Singles men women quad WC Doubles men women quad Legends men women mixed
← 2009 · US Open · 2011 →

Four-time defending champion Esther Vergeer defeated Daniela Di Toro in the final, 6–0, 6–0 to win the women's singles wheelchair tennis title at the 2010 US Open.

1. Esther Vergeer (champion)
2. Sharon Walraven (semifinals)

	Quarterfinals							Semifinals							Finals
	1	Esther Vergeer	7	7
		Florence Alix-Gravellier	5	5
								1	Esther Vergeer	6	6
									Jiske Griffioen	1	0
		Jiske Griffioen	6	6
	WC	Mackenzie Soldan	1	1
															1	Esther Vergeer	6	6
																Daniela Di Toro	0	0
		Daniela Di Toro	6	7
		Aniek van Koot	3	62
									Daniela Di Toro	6	6
								2	Sharon Walraven	4	2
		Annick Sevenans	4	3
	2	Sharon Walraven	6	6

• Main Draw