The 2010 Brier was without its two-time defending champions, the Kevin Martin Alberta rink, which did not participate in playdowns, instead focusing on the 2010 Winter Olympics. Alberta was represented for the first time by the former Canada Cup champion, Kevin Koe. Koe's brother, Jamie skipped the Northwest Territories/Yukon team for the fourth time. The 2010 was the second Brier in a row where two brothers skipped different teams (2009 was Glenn Howard vs. Russ Howard.) Glenn Howard represented Ontario once again, having won a record fifth straight provincial championship. However his brother Russ did not compete in the playdowns for New Brunswick. That province was represented by Russ' former third, James Grattan. The 1996 and 1999 Brier champion Jeff Stoughton skipped for Manitoba for the eighth time, a record for that province.[3] Former Olympic gold medalist Brad Gushue skipped for Newfoundland and Labrador for the seventh time in eight years.
Rounding out the field were Darrell McKee of Saskatchewan in his third Brier, Rod MacDonald who skipped Prince Edward Island for the third time, Brad Jacobs of Northern Ontario playing in his third Brier, Jeff Richard of British Columbia, Serge Reid of Quebec and Ian Fitzner-LeBlanc who all played their first Briers.
Kevin Koe's Alberta rink defeated Glenn Howard of Ontario in the final with a score of 6–5 to win the 2010 Tim Hortons Brier.