Singles
2010 Samarkand Challenger
Final
Champion	Andrej Martin
Runner-up	Marek Semjan
Score	6–4, 7–5
Events
Singles Doubles
← 2009 · Samarkand Challenger · 2011 →

Dustin Brown was the defending champion, but he chose to compete in Istanbul challenger instead.
Andrej Martin won the title, after won 6–4, 7–5 against his compatriot Marek Semjan in the final.

	Semifinals							Final
		Jürgen Zopp	4	6	65
	7	Marek Semjan	6	3	7
								7	Marek Semjan	4	5
								6/Q	Andrej Martin	6	7
	8	Andis Juška	4r
	6/Q	Andrej Martin	5

	First round							Second round							Quarterfinals							Semifinals
	1	B Kavčič	6	6
	WC	T Fernandes	2	2				1	B Kavčič	69	6	6
	WC	A Saidmukhamedov	2	1					C Poch-Gradin	7	3	4
		C Poch-Gradin	6	6											1	B Kavčič	6	5	5
		D Molchanov	3	2												J Zopp	1	7	7
		J Zopp	6	6					J Zopp	6	7
		A Flock	6	3	1			5	E Kirillov	3	67
	5	E Kirillov	4	6	6																		J Zopp	4	6	65
	3	A Kuznetsov	6	6																		7	M Semjan	6	3	7
		J Minář	4	4				3	A Kuznetsov	3	6	4
		J Statham	5	5					V Rudnev	6	2	6
		V Rudnev	7	7												V Rudnev	4	64
	WC	M Inoyatov	6	6											7	M Semjan	6	7
		A Kumantsov	4	0				WC	M Inoyatov	4	2
		J-M Valverde	3	3				7	M Semjan	6	6
	7	M Semjan	6	6

	First round							Second round							Quarterfinals							Semifinals
	8	A Juška	6	2	6
	Q	A Michon	4	6	3			8	A Juška	6	7
		A Kedryuk	6	4	3				M Ledovskikh	4	61
		M Ledovskikh	4	6	6										8	A Juška	7	6
	WC	V Uzakov	3	4												M Venus	62	3
	Q	L Grigelis	6	6				Q	L Grigelis	6	3	63
		M Venus	6	7					M Venus	2	6	7
	4	G Rufin	2	66																		8	A Juška	4r
	6/Q	A Martin	7	63	6																	6/Q	A Martin	5
	Q	A Smirnov	5	7	3			6/Q	A Martin	6	6
		M Elgin	6	5	7				M Elgin	2	3
	SE	W-s Jun	2	7	5										6/Q	A Martin	7	6
		B Pašanski	6	6												T-h Yang	5	3
		D Blömke	4	4					B Pašanski	4	1
		T-h Yang	6	6					T-h Yang	6	6
	2	Ó Hernández	1	2

• Main Draw
• Qualifying Draw