Singles
2010 Challenger Ciudad de Guayaquil
Final
Champion	Paul Capdeville
Runner-up	Diego Junqueira
Score	6–3, 3–6, 6–3
Events
Singles Doubles
← 2009 · Challenger Ciudad de Guayaquil · 2011 →

Nicolás Lapentti was the defending champion; however, he retired from professional tennis before this tournament.
Paul Capdeville won the title, defeating Diego Junqueira 6–3, 3–6, 6–3 in the final.

	Semifinals							Final
	1	Carlos Berlocq	3	5
		Diego Junqueira	6	7
									Diego Junqueira	3	6	3
									Paul Capdeville	6	3	6
		Paul Capdeville	7	3	6
	7	Máximo González	64	6	2

	First round							Second round							Quarterfinals							Semifinals
	1	C Berlocq	6	6
	Q	G Naso	0	3				1	C Berlocq	6	6
		R Farah	6	6					R Farah	3	0
	WC	JC Campozano	4	1											1	C Berlocq	6	6
		A Gensse	6	6											8	É Prodon	2	2
	WC	E Gómez	4	4					A Gensse	3	5
	Q	B Balleret	2	4				8	É Prodon	6	7
	8	É Prodon	6	6																		1	C Berlocq	3	5
	3	J Souza	6	6																			D Junqueira	6	7
	WC	R Quiroz	1	2				3	J Souza	7	4	4
		D Junqueira	6	1	7				D Junqueira	5	6	6
		R Hocevar	3	6	5											D Junqueira	1
		J Aguilar	6	6											6	M Daniel	4	r
	Q	Andrea Arnaboldi	2	4					J Aguilar	3	2
		S González	4	2				6	M Daniel	6	6
	6	M Daniel	6	6

	First round							Second round							Quarterfinals							Semifinals
	5	G Žemlja	6	66	6
		C Salamanca	3	7	3			5	G Žemlja	4	3
		P Capdeville	6	6					P Capdeville	6	6
		JS Cabal	1	4												P Capdeville	0	7	6
		G Rufin	4	6	7											G Lapentti	6	5	4
		M Alund	6	2	62				G Rufin	w/o
		G Lapentti	64	6	6				G Lapentti
	4	H Zeballos	7	4	4																		P Capdeville	7	3	6
	7	M González	6	5	7																	7	M González	64	6	2
		L Tavares	4	7	5			7	M González	6	6
	WC	E Nunez	3	5					V Estrella	2	0
		V Estrella	6	7											7	M González	7	6
	Q	M Vassallo Argüello	7	6												R Dutra da Silva	62	0
		F Bagnis	5	1				Q	M Vassallo Argüello	6	r
		R Dutra da Silva	6	7					R Dutra da Silva	6
	2	B Dabul	4	5

• Main Draw
• Qualifying Draw