2005 U.S. Men's Clay Court Championships
Date	April 18–25
Edition	37th
Category	International Series
Draw	32S / 16D
Prize money	$355,000
Surface	Clay / outdoor
Location	Houston, Texas, US
Champions
Singles
Andy Roddick[1]
Doubles
Mark Knowles / Daniel Nestor[2]
← 2004 · U.S. Men's Clay Court Championships · 2006 →

The 2005 U.S. Men's Clay Court Championships was an Association of Tennis Professionals men's tennis tournament held in Houston, Texas in the United States. The event was played on outdoor clay courts and was part of the International Series of the 2005 ATP Tour. It was the 37th edition of the tournament and was held from April 18 to April 25, 2005. First-seeded Andy Roddick won the singles tournament.

Andy Roddick defeated Sébastien Grosjean 6–2, 6–2

• It was Roddick's 2nd title of the year and the 19th of his career.

Mark Knowles / Daniel Nestor defeated Martín García / Luis Horna 6–3, 6–4

• It was Knowles's 2nd title of the year and the 37th of his career. It was Nestor's 2nd title of the year and the 39th of his career.

• Association of Tennis Professionals (ATP) – tournament profile