The 2005 Internazionali Femminili di Palermo was a professional women's tennis tournament played on outdoor clay courts. It was the 18th edition of the tournament which was part of the WTA Tier IV category of the 2005 WTA Tour. It took place in Palermo, Italy between 18 and 24 July 2005. Third-seeded Anabel Medina Garrigues won her second consecutive singles title at the event, and third in total, and earned $22,000 first-prize money.[1][2]