2,4,6-Tris(dimethylaminomethyl)phenol is an aromatic organic chemical that has tertiary amine and phenolic hydroxyl functionality in the same molecule.[1] The formula is C15H27N3O and the CAS Registry Number is 90-72-2. It is REACH registered and the European Community Number is 202-013-9.[2][3][4]
A key use is as a catalyst for epoxy resin chemistry. It can be used as a homopolymerization catalyst for epoxy resins and also as an accelerator with epoxy resin curing agents. It is then further used in coatings,[5] sealants, composites,[6] adhesives[7] and elastomers. It has been stated that it is probably the most widely used room temperature accelerator for two-component epoxy resin systems.[8][9] The kinetics of curing with and without this accelerator have been extensively studied.[10][11] It is the usual benchmark or control used when other catalysts and accelerators are being developed and tested.[12]
In addition to its use in epoxy chemistry, it is also used in polyurethane chemistry for example by grafting the molecule into the polymer backbone.[13] It is also used as a trimerization catalyst with polymeric MDI.[14]
Polyether ether ketones may also be grafted with the molecule which then finds use in lithium batteries.[15]
The high functionality of the molecule means it can be used to complex some transition metals and this has also been studied.[16]
Often cited weaknesses are yellowing and odor.[17]
The material is a Mannich base and is manufactured by reacting phenol, formaldehyde and dimethylamine in a reactor under vacuum and removing the water produced.
It is classed as a high volume chemical and as such, its toxicity profile has been extensively studied.[18][19][20]
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