The 1988 Virginia Slims of New England Women's singletennis tournament was won by Martina Navratilova. Pam Shriver was the defending champion but lost in the second round.
Navratilova won in the final 6–7, 6–4, 6–3 against Zvereva.
Seeds
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.