Women's singles
1981 U.S. Clay Court Championships
Final
Champion	Andrea Jaeger
Runner-up	Virginia Ruzici
Score	6–1, 6–0
Details
Draw	56
Seeds	14
Events
Singles men women Doubles men women
← 1980 · U.S. Clay Court Championships · 1982 →

Top-seed Andrea Jaeger won the final and $27,500 first prize money by defeating second-seeded Virginia Ruzici in the final.^[1]

The top eight seeds received a bye into the second round. A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.

	Quarterfinals							Semifinals							Final
	1	Andrea Jaeger	6	6	6
	6	Sue Barker	1	7	2
								1	Andrea Jaeger	6	6
								3	Mima Jaušovec	3	1
	3	Mima Jaušovec	4	6	7
	8	Anne Smith	6	1	5
															1	Andrea Jaeger	6	6
															2	Virginia Ruzici	1	0
		Hana Strachoňová	3	1
	4	Regina Maršíková	6	6
								4	Regina Maršíková	6	0
								2	Virginia Ruzici	7	6
		Susan Mascarin	3	6	5
	2	Virginia Ruzici	6	0	7

	First round							Second round							Third round							Quarterfinals
								1	A Jaeger	6	6
		K Sands	4	2				Q	D Rubin	0	1
	Q	D Rubin	6	6											1	A Jaeger	6	6
		R Richards	6	6												R Richards	3	0
		M Pinterová	2	2					R Richards	4	6	6
		D Jevans	1	2				11	A White	6	2	1
	11	A White	6	6																		1	A Jaeger	6	6	6
	Q	L Doherty	2	5																		6	S Barker	1	7	2
		R Tomanová	6	7					R Tomanová	6	4	6
		K Skronská	6	4	6				K Skronská	2	6	3
		A Henricksson	3	6	2											R Tomanová	4	7	4
		K Jones	6	5	2										6	S Barker	6	6	6
		Y Brzáková	2	7	6				Y Brzáková	4	1
								6	S Barker	6	6

	First round							Second round							Third round							Quarterfinals
								3	M Jaušovec	6	6
		S Jaeger	2	1					J DuVall	2	4
		J DuVall	6	6											3	M Jaušovec	6	6
	Q	F Raschiatore	2	0												P Vásquez	3	3
		P Vásquez	6	6					P Vásquez	6	6
		A-M Fernandez	6	6					A-M Fernandez	4	1
	10	S Collins	1	2																		3	M Jaušovec	4	6	7
	14	K Rinaldi	6	6																		8	A Smith	6	1	5
	Q	Cissie Donigan	1	3				14	K Rinaldi	6	6
	Q	E Burgin	6	6				Q	E Burgin	2	2
		R Fairbank	2	3											14	K Rinaldi	4	4
	Q	K Steinmetz	6	6											8	A Smith	6	6
		G Coles	1	3				Q	K Steinmetz	1	3
								8	A Smith	6	6

	First round							Second round							Third round							Quarterfinals
								5	D Fromholtz	5	1
		B Norton	6	6					B Norton	7	6
		L duPont	3	3												B Norton	6	6	1
		H Strachoňová	4	6	6											H Strachoňová	2	7	6
		D Gilbert	6	0	2				H Strachoňová	6	6
	LL	B Remilton	5	0				12	K Horvath	2	1
	12	K Horvath	7	6																			H Strachoňová	3	1
		D Freeman	3	6	7																	4	R Maršíková	6	6
		A Moulton	6	2	5				D Freeman	2	4
		P Smith	5	2					V Nelson	6	6
		V Nelson	7	6												V Nelson	2	1
		K Cummings	6	6											4	R Maršíková	6	6
		N Gregory	2	3					K Cummings	2	1
								4	R Maršíková	6	6

	First round							Second round							Third round							Quarterfinals
								7	J Russell	4	6	6
		K Keil	5	7	6				K Keil	6	2	1
		I Budařová	7	6	2										7	J Russell	5	5
		L Duk-hee	4	6	1											S Mascarin	7	7
		S Mascarin	6	3	6				S Mascarin	6	5	6
		Y Vermaak	6	6	2			9	M L Piatek	4	7	1
	9	M L Piatek	1	7	6																		S Mascarin	3	6	5
	13	P Casale	6	6																		2	V Ruzici	6	0	7
		S Saliba	2	1				13	P Casale	6	6
		B Jordan	6	6					B Jordan	0	2
	Q	H Ludloff	3	2											13	P Casale	5	1
		J Portman	1	1											2	V Ruzici	7	6
		P Medrado	6	6					P Medrado	3	4
								2	V Ruzici	6	6