The 1948 South Sydney was the 41st in the club's history. The club competed in the New South Wales Rugby Football League Premiership (NSWRFL), finishing the season 7th, missing the finals.

	Team	Pld	W	D	L	PF	PA	PD	Pts
1	Western Suburbs (P)	18	16	0	2	322	189	+133	32
2	Newtown	18	13	0	5	386	248	+138	26
3	Balmain	18	12	2	4	287	222	+65	26
4	St. George	18	10	1	7	332	262	+70	21
5	Canterbury-Bankstown	18	7	2	9	282	276	+6	16
6	Eastern Suburbs	18	7	2	9	225	248	-23	16
7	South Sydney	18	7	1	10	265	302	-37	15
8	Parramatta	18	5	1	12	237	346	-109	11
9	Manly-Warringah	18	4	1	13	221	334	-113	9
10	North Sydney	18	3	2	13	191	321	-130	8

Round	Opponent	Result	Score	Date	Venue	Ref
1	Parramatta	Win	15 – 12	Saturday 10 April	Cumberland Oval	[1]
2	Eastern Suburbs	Draw	19 – 19	Saturday 17 April	Redfern Park	[2]
3	Western Suburbs	Loss	8 – 10	Saturday 24 April	Sydney Cricket Ground	[3]
4	Balmain	Loss	10 – 13	Monday 26 April	Leichhardt Oval	[4]
5	Newtown	Loss	8 – 16	Saturday 1 May	Erskineville Oval	[5]
6	Manly-Warringah	Win	17 – 9	Saturday 5 June	Redfern Park	[6]
7	North Sydney	Win	12 – 7	Saturday 12 June	North Sydney Oval	[7]
8	Canterbury-Bankstown	Loss	8 – 17	Monday 14 June	Sydney Cricket Ground	[8]
9	St. George	Loss	2 – 31	Saturday 19 June	Redfern Park	[9]
10	Parramatta	Win	38 – 5	Saturday 26 June	Redfern Park	[10]
11	Eastern Suburbs	Win	16 – 8	Saturday 3 July	Sports Ground	[11]
12	Western Suburbs	Loss	17 – 18	Saturday 10 July	Sydney Cricket Ground	[12]
13	Balmain	Loss	8 – 14	Saturday 17 July	Redfern Park	[13]
14	Newtown	Loss	13 – 20	Saturday 24 July	Redfern Oval	[14]
15	Manly-Warringah	Loss	13 – 39	Saturday 31 July	Brookvale Oval	[15]
16	North Sydney	Win	24 – 17	Saturday 7 August	Redfern Park	[16]
17	Canterbury-Bankstown	Win	22 – 16	Saturday 14 August	Redfern Park	[17]
18	St. George	Loss	15 – 31	Saturday 21 August	Hurstville Oval	[18]