The year 1624 in science and technology involved some significant events.

• Jakob Bartsch's star atlas^[1] is the first to depict six recently discovered constellations, including Camelopardalis around the North Star.

• July or August – Portuguese Jesuit priest António de Andrade becomes the first European to enter Tibet.

• Henry Briggs publishes Arithmetica Logarithmica.
• Edmund Gunter produces The description and use of sector, the cross-staffe, and other instruments for such as are studious of mathematical practise, notable for being published in English as a practical text.^[2]

• Adriaan van den Spiegel, in De semitertiana libri quatuor, gives the first comprehensive description of malaria.

• 12 September – Cornelis Drebbel demonstrates his third submarine on the River Thames in England.
• The 15-arch Berwick Bridge in Great Britain by James Burrell is opened to traffic.

• 25 May – The Parliament of England passes the Statute of Monopolies, requiring patent monopolies to show novelty.^[3]
• The Parlement of France passes a decree forbidding criticism of Aristotle on pain of death.^[4]

• 10 September – Thomas Sydenham, English physician, the first person to recommend the use of quinine for relieving symptoms of malaria (died 1689)

• Giuseppe Biancani, Italian astronomer (born 1566)
• 5 December – Gaspard Bauhin, Swiss botanist and physician who developed an important early plant classification system (born 1560)
• 26 December – Simon Marius, German astronomer (born 1573)^[5]