The railway station of Islahiye is the last stop on the railway to Damascus in Syria. Since March 2001, a regular train line runs once a week between Syria and Iran via Islahiye.[5] The state road D.825, which connects Gaziantep with Antakya, runs through İslahiye.
The town is inhabited by Yörüks of the Aydınlı tribe.[6] English traveler Mark Sykes recorded İslahiye as a town inhabited by Turks in early 20th century.[7]
A magnitude 7.8 earthquake struck İslahiye on 6 February 2023, causing widespread devastation in the town and many deaths.[8]