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(a) SCF contains three core subunits—the RING protein Rbx1, the cullin Cul1, and Skp1. Rbx1 binds the E2–ubiquitin conjugate. The target protein binds to an F-box protein that is bound to the enzyme core via interactions with the Skp1 subunit. After binding of a target protein to the F-box protein, the ubiquitin is transferred from E2 and attached via a peptide bond to a lysine side chain in the target protein. (b) A composite model structure for human SCF derived from X-ray structures of...

Bahadur Shah I قطب الدین محمد بہادر شاهBadhishah-I-HindustaniKaisar Mughal ke-7 dari IndiaBerkuasa19 Juni 1707 – 27 Februari 1712Penobatan19 Juni 1707 di DelhiPendahuluMuhammad Azam ShahPenerusJahandar ShahInformasi pribadiKelahiran14 Oktober 1643Burhanpur, Kemaharajaan MughalKematian27 Februari 1712(1712-02-27) (umur 68)Lahore, Kemaharajaan MughalPemakamanMasjid Moti, DelhiNama lengkapAbul-nasr Sayyid Qutb-ud-din Muhammad Shah Alam Bahadur Shah BadshahNama anu...

Chemical compound EtodroxizineClinical dataATC codeNoneLegal statusLegal status BR: Class C1 (Other controlled substances)[1] Identifiers IUPAC name 2-[2-(2-{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)ethoxy]ethanol CAS Number17692-34-1PubChem CID63345ChemSpider57011UNIICI1S3XAK7OChEMBLChEMBL2104263Chemical and physical dataFormulaC23H31ClN2O3Molar mass418.96 g·mol−13D model (JSmol)Interactive image SMILES c1ccc(cc1)C(c2ccc(cc2)Cl)N3CCN(CC3)CCOCCOCCO InChI In...

Pseudoscientific claims of past alien contact This article is about the idea that aliens visited ancient humans. For the idea that aliens seeded life on earth, see Directed panspermia. This article is about the real-life topic. For the plot device from works of fiction, see Ancient astronauts in popular culture. Ancient astronautsPetroglyphs from Val Camonica, Italy. Ancient astronaut proponents believe that these pictures resemble modern astronauts.ClaimsIntelligent extraterrestrial life vis...

Pertempuran Kuruc-Labanc Kuruc (bahasa Hungaria: [ˈkurut͡s], jamak kurucok), juga dieja kurutz,[1][2][3] adalah para pemberontak anti-Habsburg di Kerajaan Hungaria dari tahun 1671 hingga 1711. Pasukan kuruc terdiri dari para petani dan hamba, termasuk petani-petani Protestan Hungaria.[4] Terdapat pula petani Slavia yang tergabung dalam kelompok ini.[5] Kelompok ini dikenal karena telah melancarkan perang kemerdekaan besar melawan dominasi Habsbur...

Niles FitchFitch tahun 2019Lahir12 Juli 2001 (umur 22)Atlanta, Georgia, Amerika SerikatPekerjaanAktorTahun aktif2011–sekarang Niles Fitch (lahir 12 Juli 2001) adalah aktor asal Amerika Serikat yang memulai karirnya sebagai aktor cilik. Ia menjadi terkenal melalui perannya dalam serial NBC, This Is Us. Ia mendapat pujian atas perannya sebagai Quinton dalam film drama The Fallout (2021). Kehidupan pribadi Fitch lahir di Atlanta, Georgia dari pasangan Frederick dan Nakata Fitch. Nil...

1967 Philippine constitutional plebiscite November 14, 1967 Are you in favor of increasing the number of congressmen from 120 to 180?OutcomeProposal rejectedResults Choice Votes % Yes 737,997 18.28% No 3,299,485 81.72% Total votes 4,037,482 100.00% Registered voters/turnout 9,744,604 41.43% Results by province and city Yes:  50–60%  60–70%  70–80%   80–90%  90-100% No:  50–60%  60–70%  70–80%  ...

Catholic school in Staten Island, New York, United StatesMoore Catholic High SchoolAddress100 Merrill AvenueStaten Island, New York 10314United StatesCoordinates40°36′35″N 74°9′52″W / 40.60972°N 74.16444°W / 40.60972; -74.16444InformationFormer nameCountess Moore High School (until 1978)TypeCatholicReligious affiliation(s)Roman CatholicEstablished1962 (62 years ago) (1962)FounderRoman Catholic Archdiocese of New York; Presentation Sisters of ...

This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Herri Urrats – news · newspapers · books · scholar · JSTOR (March 2012) (Learn how and when to remove this template message) Herri UrratsHerri Urrats festival held in 2011GenreBasque cultureDate(s)Second Sunday of MayFrequencyAnnualLocation(s)Saint-Pée-sur-Niv...

Keakuratan artikel ini diragukan dan artikel ini perlu diperiksa ulang dengan mencantumkan referensi yang dapat dipertanggungjawabkan. Diskusi terkait dapat dibaca pada the halaman pembicaraan. Harap pastikan akurasi artikel ini dengan sumber tepercaya. Lihat diskusi mengenai artikel ini di halaman diskusinya. (Pelajari cara dan kapan saatnya untuk menghapus pesan templat ini) Nama ini menggunakan cara penamaan Spanyol: nama keluarga pertama atau paternalnya adalah Hernández dan nama ke...

† Человек прямоходящий Научная классификация Домен:ЭукариотыЦарство:ЖивотныеПодцарство:ЭуметазоиБез ранга:Двусторонне-симметричныеБез ранга:ВторичноротыеТип:ХордовыеПодтип:ПозвоночныеИнфратип:ЧелюстноротыеНадкласс:ЧетвероногиеКлада:АмниотыКлада:Синапсиды�...

ÇartəpəMunisipalitasÇartəpəKoordinat: 41°26′N 48°29′E / 41.433°N 48.483°E / 41.433; 48.483Koordinat: 41°26′N 48°29′E / 41.433°N 48.483°E / 41.433; 48.483Negara AzerbaijanRayonQubaPopulasi[butuh rujukan] • Total706Zona waktuUTC+4 (AZT) • Musim panas (DST)UTC+5 (AZT) Çartəpə (juga Chartapa dan Chartepe) adalah sebuah desa dan munisipalitas di Rayon Quba, Azerbaijan. Desa ini memiliki pe...

Uruguayan footballer and coach (1917-2004) In this Spanish name, the first or paternal surname is Máspoli and the second or maternal family name is Arbelvide. Roque Máspoli Máspoli as Peñarol goalkeeperPersonal informationFull name Roque Gastón Máspoli ArbelvideDate of birth (1917-10-12)12 October 1917Place of birth Montevideo, UruguayDate of death 22 February 2004(2004-02-22) (aged 86)Place of death Montevideo, UruguayHeight 1.89 m (6 ft 2 in)Position(s) Goa...

この記事は検証可能な参考文献や出典が全く示されていないか、不十分です。出典を追加して記事の信頼性向上にご協力ください。（このテンプレートの使い方）出典検索?: コルク – ニュース · 書籍 · スカラー · CiNii · J-STAGE · NDL · dlib.jp · ジャパンサーチ · TWL（2017年4月） コルクを打ち抜いて作った瓶の栓 コルク（木栓、�...

Allmannsweilercomune Allmannsweiler – Veduta LocalizzazioneStato Germania Land Baden-Württemberg DistrettoTubinga CircondarioBiberach TerritorioCoordinate48°01′42″N 9°35′37″E / 48.028333°N 9.593611°E48.028333; 9.593611 (Allmannsweiler)Coordinate: 48°01′42″N 9°35′37″E / 48.028333°N 9.593611°E48.028333; 9.593611 (Allmannsweiler) Altitudine625 m s.l.m. Superficie4,10 km² Abitanti335[1] (31-12-2022) D...

† Палеопропитеки Научная классификация Домен:ЭукариотыЦарство:ЖивотныеПодцарство:ЭуметазоиБез ранга:Двусторонне-симметричныеБез ранга:ВторичноротыеТип:ХордовыеПодтип:ПозвоночныеИнфратип:ЧелюстноротыеНадкласс:ЧетвероногиеКлада:АмниотыКлада:СинапсидыКласс:�...

This article needs to be updated. Please help update this article to reflect recent events or newly available information. (July 2015) Map of Libya Tripoli, capital of Libya Sabratha Misurata Derna Tobruk Sirte Ghadames Tajura Ubari This is a list of the 100 largest populated places in Libya. Some places in the list could be considered suburbs or neighborhoods of some large cities in the list, so this list is not definitive. No. City Population 1 Tripoli / طرابلس الغرب 2,220,000&#...

I'll Try Something NewSingle by The Miraclesfrom the album I'll Try Something New B-sideYou Never Miss a Good ThingReleasedApril 9, 1962RecordedHitsville USA (Studio A); 1961–1962GenreSoul, popLength3:00LabelTamlaT 54059Songwriter(s)Smokey RobinsonProducer(s)Smokey Robinson Berry GordyThe Miracles singles chronology What's So Good About Goodbye (1961) I'll Try Something New (1962) You've Really Got a Hold on Me (1962) AudioI'll Try Something New by The Miracles on YouTube I'll Try Something...

Навчально-науковий інститут інноваційних освітніх технологій Західноукраїнського національного університету Герб навчально-наукового інституту інноваційних освітніх технологій ЗУНУ Скорочена назва ННІІОТ ЗУНУ Основні дані Засновано 2013 Заклад Західноукраїнський �...

Australian newspapers The Countryman redirects here. For the British magazine, see Countryman (magazine). 7 April 1927 edition, with the Countryman behind The Western Mail, or Western Mail, was the name of two weekly newspapers published in Perth, Western Australia. Published 1885–1955 The 1897 Christmas Number The first Western Mail was published on 19 December 1885[1] by Charles Harper and John Winthrop Hackett, co-owners of The West Australian, the state's major daily paper. It w...